Moderna's bivalent boosters trigger strong antibody response against latest subvariants Coronavirus Disease COVID Omicron Vaccine bivalent SARSCoV2 moderna_tx
By Benedette Cuffari, M.Sc.Nov 14 2022Reviewed by Aimee Molineux Due to the continuous emergence of new immune evasive and more pathogenic variants of the severe acute respiratory syndrome coronavirus 2 , current coronavirus disease 2019 vaccines have become less effective in preventing infection. As a result, Moderna has developed a novel bivalent vaccine that has recently been shown to elicit superior immune responses against these novel viral variants.
Despite these efforts, several studies have shown that three doses of current mRNA vaccines provide only partial protection against SARS-CoV-2 infection with the Omicron variant. Related StoriesTaken together, a total of 819 people have participated in this study to date. Of these individuals, 437 study participants were assigned to receive the novel bivalent vaccine dose, whereas 377 received a second booster dose of the original Moderna mRNA-1273 vaccine.
Brasil Últimas Notícias, Brasil Manchetes
Similar News:Você também pode ler notícias semelhantes a esta que coletamos de outras fontes de notícias.
What is the post-COVID-19-associated morbidity in German children, adolescents, and adults?Researchers investigated coronavirus disease 2019 (COVID-19)-associated morbidity in children, adolescents, and adults using healthcare data covering ~46% of the German population.
Consulte Mais informação »
More adverse reactions following bivalent COVID-19 mRNA booster vaccineMore adverse reactions following bivalent COVID-19 mRNA booster vaccine Vaccine Coronavirus Disease COVID bivalent medrxivpreprint Uni_WUE UniofOxford
Consulte Mais informação »
Timing and Trends for Municipal Wastewater, Lab-Confirmed Case, and Syndromic Case Surveillance of COVID-19 in Raleigh, North CarolinaObjectives. To compare 4 COVID-19 surveillance metrics in a major metropolitan area. Methods. We analyzed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in wastewater influent and primary solids in Raleigh, North Carolina, from April 10 through December 13, 2020. We compared wastewater results with lab-confirmed COVID-19 cases and syndromic COVID-like illness (CLI) cases to answer 3 questions: (1) Did they correlate? (2) What was the temporal alignment of the different surveillance systems? (3) Did periods of significant change (i.e., trends) align? Results. In the Raleigh sewershed, wastewater influent, wastewater primary solids, lab-confirmed cases, and CLI were strongly or moderately correlated. Trends in lab-confirmed cases and wastewater influent were observed earlier, followed by CLI and, lastly, wastewater primary solids. All 4 metrics showed sustained increases in COVID-19 in June, July, and November 2020 and sustained decreases in August and September 2020. Conclusions. In a major metropolitan area in 2020, the timing of and trends in municipal wastewater, lab-confirmed case, and syndromic case surveillance of COVID-19 were in general agreement. Public Health Implications. Our results provide evidence for investment in SARS-CoV-2 wastewater and CLI surveillance to complement information provided through lab-confirmed cases. (Am J Public Health. Published online ahead of print November 10, 2022:e1–e11. https://doi.org/10.2105/AJPH.2022.307108)
Consulte Mais informação »
Severe Neuro-COVID is associated with peripheral immune signatures, autoimmunity and neurodegeneration: a prospective cross-sectional study - Nature CommunicationsBoth acute and chronic COVID-19 disease (also known as long-COVID) may affect the central nervous system. Here authors characterize the immunological profile of peripheral blood and cerebrospinal fluid of COVID-19 patients in order to identify the main factors that contribute to neurological impairment and the severity of neurological symptoms in Sars-CoV-2 infection.
Consulte Mais informação »
Long-term humoral response and its determinants following 2- and 3-dose COVID-19 mRNA vaccinesResearchers compared the waning of vaccine-induced immunity from two and three doses of mRNA COVID-19 Pfizer-BioNTech vaccine BNT162b2 by conducting a repeated serological study to assess the prolonged humoral response.
Consulte Mais informação »
Department for Education shows Lancashire secondary school pupils fell further behind their classmates during CovidDisadvantaged secondary school pupils in Lancashire fell further behind their classmates during the pandemic, new figures have shown.
Consulte Mais informação »