What is the post-COVID-19-associated morbidity in German children, adolescents, and adults? Medizin_TUD COVID19 SARSCoV2 Morbidity
By Neha MathurNov 14 2022Reviewed by Aimee Molineux In a recent study published in Plos Medicine, researchers investigated coronavirus disease 2019 -associated morbidity in children, adolescents, and adults using healthcare data covering ~46% of the German population.
About the study In the present study, researchers obtained data from German statutory health insurance companies for 1 January 2019 to 31 December, 2020. They identified individuals with reverse transcription-polymerase chain reaction -confirmed COVID-19, and the date of their first diagnosis served as the index date for both cohorts. The control cohort had individuals who matched 1:5 based on age, gender, and comorbidity-based propensity score.
Study findings The study population comprised 157,134 individuals, of which 11,950 were children, including adolescents, and 145,184 were adults; also, 48.1% and 60.2% of these were females, respectively. While adolescents were in the zero to 11 years age group, adults were in the age group of 18 to 49 years. The mean follow-up time for children/adolescents and adults was 236 days and 254 days, respectively.
Although the estimated long-term sequelae of COVID-19 appear to be less pronounced in children and adolescents in absolute terms, high infection rates emphasize that post-COVID-19 cannot be dismissed among children and adolescents.
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