Unveiling long COVID: new study explores symptoms and strain variations Life_MDPI longcovid covid COVID19 SARSCoV2 longCOVID symptoms strain
By Dr. Chinta SidharthanJul 17 2023Reviewed by Lily Ramsey, LLM In a recent study published in the Life Journal, researchers investigated the variation in the clinical and demographic characteristics of acute severe acute respiratory syndrome coronavirus 2 and the persistence of long coronavirus disease across different strains of SARS-CoV-2.
Long COVID's physical and mental symptoms have been shown to affect the quality of life, with low energy levels and pain preventing the patients from conducting their daily activities. Related StoriesPatients above the age of 18 years diagnosed with symptomatic SARS-CoV-2 infections confirmed using positive swab tests were eligible to participate in the study, and patients were excluded if they could not read and provide informed consent.
Hospitalization, mechanical ventilation, and oxygen supplementation requirements were used to classify COVID-19 severity on a scale of one to four, with one indicating no hospitalization and four indicating hospitalizations with the need for Intermittent Mandatory Ventilation. Infections between February and June 2021 were attributed to the Alpha, Beta, Gamma, and Delta variants, but the Delta variant was considered solely responsible for infections between July and November 2021. All infections after December 2021 till the end of the study period in March 2022 were classified as SARS-CoV-2 Omicron infections.
Furthermore, the multi-variable analysis indicated that persistent symptoms during long COVID are positively associated with the number of symptoms during the onset of the acute SARS-CoV-2 infection, which could be linked to a persistent state of inflammation.
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