When depression and ADHD go together, symptoms can be more severe. Learn the different therapies and treatment options available to you.
These medications target things that are very different than all of those other classes of depression medication, and are the result of our ever-growing understanding that depression is nuanced and not the same for every patient.
While not FDA-approved, off-label lithium is used by some psychiatrists to augment depression treatment as well., but this treatment can be especially effective for certain patients. As for TRD patients, research indicates that ECT can be a safe, helpful intervention in high-risk situations. A pregnant patient of mine, for example, was struggling with bipolar illness and was at high risk for suicide, but she could not take medication without it interfering with her pregnancy. She underwent electroconvulsive therapy instead, and it was amazingly helpful for her.
Patients who undergo TMS can proceed with normal activities right after sessions. Some side effects, however, may include scalp discomfort, lightheadedness, slight twitching, and, rarely, seizures. There are no cognitive functioning side effects, like memory loss or confusion, associated with the procedure. This treatment is not indicated for patients with any metal in the body, or for people with psychosis.
Ketamine promotes synaptic connections within the brain for learning and memory, but it can also block other receptors, leading to rapid antidepressant action. Studies have shown that the drug reduces or eliminates very acute or distressing symptoms of depression, including suicidal thoughts. Other studies show that 60 percent or more of patients find relief from depressive symptoms with these infusions.
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