Shaping the human metabolome: the impact of a ketogenic diet LMU_Muenchen ketodiet ketogenic ketogenicdiet diet microbiome metabolome
By Bhavana KunkalikarJun 6 2023Reviewed by Lily Ramsey, LLM In a recent study published in the Clinical Nutrition Journal, researchers explored how the human metabolic fingerprint changes with a ketogenic diet .
About the study In the present study, researchers explored the alterations in the metabolome of healthy individuals after a KD. Volunteers followed a WD before enrolling. The KD involves limiting carbohydrate intake to 10% of daily caloric intake while increasing the proportion of fats and proteins. Results During the three-week diet, healthy volunteers followed the KD and were able to produce ketone bodies as expected. No unintended effects or adverse events were observed. The participants experienced a slight weight loss throughout the diet, with a median reduction in body mass index of 0.69 kg/m2, which translates to a 2.9% decrease.
Furthermore, the serum urea concentration was increased in individuals following a KD. No significant associations were found in the correlation analysis, indicating that the changes observed were not linked to weight loss.
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