At one time or another, we’ve all felt paralyzed by a threat or danger. Now scientists have traced where that reaction to a threat arises. In a new study, University of Iowa researchers confirmed a neural circuit linking two separate regions in the brain governs how animals, including humans, rea
Researchers identified neural circuit linking two separate regions in the brain governs how animals, including humans, react to a stressful situation.Now scientists have traced where that reaction to a threat arises. In a new study,researchers confirmed a neural circuit linking two separate regions in the brain governs how animals, including humans, react to a stressful situation.
“A lot of chronic stress diseases, like depression and anxiety disorders, are associated with what we call a passive coping behavior,” explains Jason Radley, associate professor in the Department of Psychological and Brain Sciences and the study’s corresponding author. “We know that a lot of these conditions are caused by life stress. The simplest reason we’re interested in this pathway is thinking about it as a circuit that can promote resilience against stress.
“What that means is by activating the pathway, we saw broad stress-buffering effects,” Radley says. “It not only revived the rats’ active coping behaviors, it also restored them and greatly decreased stress hormone release.”
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