Does a vasectomy change the semen microbiome? MensHealth Microbiome Vasectomy Seminal Dysbiosis univmiami TexasTech MontefioreNYC wakeforestmed JeffersonUniv
By Dr. Priyom Bose, Ph.D.Nov 22 2022Reviewed by Benedette Cuffari, M.Sc. The microbiome consists of symbiotic, pathogenic, and commensal microorganisms that inhabit the human body and contribute to its health and disease status. Recent technological advancements have helped elucidate the metabolic functions, symbiotic states, and mode of interaction of these bacterial organisms with host cells.
Previous studies have shown that Lactobacillus and Gardnerella are the two most abundant bacteria in high-quality sperm, whereas Prevotella is abundantly found in low-quality sperm. This prospective study included 58 outpatient men grouped based on various treatments and procedures. Group 1 consisted of 22 men who underwent fertility evaluation and were found to have normozoospermic semen, as defined by normal sperm count and motility.
Study findings A total of 76 semen samples were obtained from 58 participants. About 89% of the study cohort were Caucasian, and 50% were non-Hispanic. No participants experienced intraoperative or postoperative complications. Vasectomized semen samples revealed reduced a-diversity and showed a high possibility of lacking spermatozoa. This was similar to nonobstructive azoospermia ; however, more research is required to elucidate the underlying mechanism for this condition.
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