Did COVID-19-associated lockdowns increase the rate of memory decline in patients with cognitive impairments? AlzheimersRes AlzheimerAms covid COVID-19 SARS-CoV-2 memory decline cognative impairments lockdown quarantine lastingeffects
By Dr. Chinta SidharthanApr 18 2023Reviewed by Lily Ramsey, LLM In a recent study published in the journal Alzheimer’s Research & Therapy, researchers investigated whether the coronavirus disease 2019 -associated lockdown measures had an impact on the cognitive decline rate in a clinical population comprising dementia, subjective cognitive decline , and mild cognitive impairment patients.
Cognitive impairments in most cases of MCI and some cases of SCD are associated with an underlying neurodegenerative disease. Structured situations in daily life help in the management of and often slow the progression of cognitive impairments in these diseases. The lockdown cohort included patients diagnosed with dementia with Lewy Bodies, Alzheimer’s disease, MCI, SCD, primary progressive aphasia, or frontotemporal dementia. The historical cohort included matched patients with the same diagnoses as the lockdown cohort.
The findings indicated that faster cognitive decline during the COVID-19-associated lockdowns was not observed in patients with dementia but was seen in patients with MCI and SCD. Additionally, the sudden decrease in social activity could also have exacerbated the cognitive decline in patients in pre-dementia stages.
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