Analysis of blood samples from 175 coronavirus patients released from hospital showed nearly a third had low levels of antibodies and in some patients, they could not be detected at all.
Chinese scientists are hoping to find out whether recovered coronavirus patients have a higher risk of reinfection, after finding low levels of antibodies in people discharged from hospital in a small, preliminary study.
All of the patients had recently recovered from mild symptoms of the disease and most of those with low antibody levels were young. The researchers did not include patients who had been admitted to intensive care units because many of them already had antibodies from donated blood plasma—a treatment where serum from the blood of recovered patients is given to people with the virus to provide them with COVID-19 antibodies.
Patients experiencing symptoms including a fever and a cough may have recovered from the virus using other areas of the immune system, such as T-cells of cytokines, but how this happened is unknown. The researchers also say the study also has implications for development of a vaccine. If the real virus could not induce an antibody response, the weakened version used in a vaccine may not work for some patients too.
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