Doctors prescribe anticholinergic drugs for a number of conditions, but a new study suggests they may increase the risk of dementia in older patients. What to know:
MONDAY, June 24, 2019 -- Doctors often prescribe anticholinergic drugs for a variety of ills. But a new study suggests they may increase the risk of dementia in older patients.
But the new British study found that people aged 55 and older who took strong anticholinergic medications daily for three years or more had a 50% increased risk of dementia. To find out, Coupland's team examined the medical records of nearly 59,000 patients in the U.K. with dementia, as well as a control group of more than 225,000 patients without dementia. All the patients were 55 and older. The average age of the dementia patients was 82.
In the one to 11 years before dementia diagnosis or the equivalent in controls, nearly 57% of dementia patients and 51% of people in the control group were prescribed at least one strong anticholinergic drug, with an average of six prescriptions in dementia patients and four in controls.The researchers noted that this was an observational study, so it cannot prove that anticholinergic drugs helpdementia.
And Coupland stressed that,"the risks of this type of medication should be carefully considered by health care professionals alongside the benefits when the drugs are prescribed." In some cases,"alternative treatments should be considered where possible, such as other types of antidepressants or alternative types of treatment for bladder conditions," she said.
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