Several studies suggest that an extended interval between initial dosing may help improve vaccine effectiveness and decrease the small, but potential risk of myocarditis.
The Centers for Disease Control and Prevention updated its COVID-19 vaccine guidance on Tuesday to recommend that some Americans over the age of 12 who have received a first mRNA vaccine dose, wait up to eight weeks before getting their second dose, instead of the previously recommended three to four.
Although an increased risk of myocarditis, particularly among young men, has been identified with both the Pfizer and Moderna vaccines, extensive data analysis over the course of the pandemic has shown that COVID-19 mRNA vaccines are overwhelmingly safe, not only in clinical trials, but also in the real world. The risk of myocarditis is also higher if you get COVID-19 itself than with the vaccine.
In particular, the CDC emphasized that young men, between the ages of 12-39 years, who may be at increased risk for myocarditis, should consider this extended time series.
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