Brazil's diversity makes country a testing ground for a global stem cell biobank, scientists say

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Brazil's diversity makes country a testing ground for a global stem cell biobank, scientists say
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A biobank for all, in which a person from any background could find a bone marrow donor for a stem cell transplant, is a major goal for stem cell science. While repositories of cell lines that could be a match for most patients are successfully materializing in some countries with genetically homogenous populations like Japan and the United Kingdom, how many more we need for a universal solution remains unknown. Researchers estimate at least 559 distinct cell lines would be required to cover 95% of the more diverse, and globally representative, people of Brazil.

DNA damage caused by factors such as ultraviolet radiation affect nearly three-quarters of all stem cell lines derived from human skin cells, say researchers, who argue that whole genome sequencing ...

Ten-second videos of white blood cell motion in the skin's microvasculature greatly improved the prediction of which stem cell and bone marrow transplant patients would have a relapse of their ... A potentially safer, more effective chemotherapy treatment for patients with blood-related cancers, such as leukemia, who need a particular bone marrow transplant procedure is under study. The ...

Even when chronic myelogenous leukemia is in remission, 'sleeper cell,' quiescent leukemic stem cells are maintained in microenvironments in the bone marrow. This maintenance is poorly ...

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Brazil's diversity makes country a testing ground for a global stem cell biobank, scientists sayBrazil's diversity makes country a testing ground for a global stem cell biobank, scientists sayA biobank for all, in which a person from any background could find a bone marrow donor for a stem cell transplant, is a major goal for stem cell science. While repositories of cell lines that could be a match for most patients are successfully materializing in some countries with genetically homogenous populations like Japan and the United Kingdom, how many more we need for a universal solution remains unknown. Researchers estimate at least 559 distinct cell lines would be required to cover 95% of the more diverse, and globally representative, people of Brazil.
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