The tragic deaths of 13 children in England and an unusual rise in autumn cases have put researchers on alert.
Group A streptococcal bacteria cause infections that trigger a sore throat — and can lead to scarlet fever or, rarely, more serious conditions and death.As the days lengthen and temperatures rise each spring, British paediatricians know what to expect: an increase in group A streptococcal infections that should tail off by the summer.
In rare instances, strep A can lead to a more serious condition called invasive group A streptococcal infection, particularly in people with compromised immune systems. This can cause conditions including meningitis, toxic shock syndrome and necrotizing fasciitis, a swiftly progressing infection of the tissue under the skin that is sometimes called flesh-eating disease.
England has been experiencing high levels of springtime scarlet fever for years, and in 2018 there was an “almighty surge”, says Sriskandan. Each surge brings an expansion of strains that are fitter than previously dominant versions, and one that became dominant around 2016 happened to be particularly prone to causing serious illness, she says.
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