Which aspects of sleep architecture and respiratory-related sleep disturbances are associated with cognitive function in middle-aged to older adults? JAMANetworkOpen MonashUni HarvardChanSPH UMNews PittTweet
By Neha MathurJul 20 2023Reviewed by Sophia Coveney In a recent study published in JAMA Network Open, researchers created the Sleep and Dementia Consortium, comprising five population-based cohort studies.
There are many possible mechanisms through which sleep could decrease the dementia risk. For instance, adequate and good quality sleep augments the glymphatic clearance of Alzheimer’s disease proteins, facilitating memory consolidation and synaptic remodeling. All study participants were at least 45 years old and had never had dementia or stroke. The standardized protocol for sleep assessments recorded readings from an electroencephalogram, electrooculogram, finger pulse oximeter, a single bipolar electrocardiogram, and ambient light levels, to name a few.
While global cognition was the primary study outcome, the team explored cognitive domain scores as secondary outcomes, and methods used for each varied across cohorts. So, the researchers performed a principal component analysis of all cognitive test scores to derive a general cognitive score. Results Overall, there were 5946 participants, of which 1875 were females with a median age between 58 and 89 years at PSG acquisition. Cohort-wise, there were 1791, 701, 640, 2619, and 195 participants from ARIC, CHS, FHS, MrOS, and SOF studies.
Note that N3 sleep plays a crucial role in memory consolidation as it is the period for optimizing glymphatic clearance. Yet, in this study, the researchers found no association between differences in N3 percentage and cognitive function. It is possible that other sleep stages compensated for age-related N3 declines or that single-night PSG were inadequate to quantify N3 sleep.
Brasil Últimas Notícias, Brasil Manchetes
Similar News:Você também pode ler notícias semelhantes a esta que coletamos de outras fontes de notícias.
Sleep tracking app Pokémon Sleep is now available in EuropePokémon Sleep, the new Pokémon-themed sleep tracker app for iOS and Android, is now available to download…
Consulte Mais informação »
Pokémon Sleep exploit sees players pretend to rack up weeks of sleep for Pokémon Go rewardsPokémon Sleep players with access to the game's £50 Pokémon Go Plus+ peripheral are pretending to s…
Consulte Mais informação »
Pokemon Sleep is now available in Europe | VGCPokemon-themed sleep tracking app, Pokemon Sleep, is now available in Europe.
Consulte Mais informação »
Best king size mattress in 2023: big beds for all budgetsNeed a bigger bed? Here are the best king size mattresses:
Consulte Mais informação »
Lawyer jailed for embezzling £120,000 from pensioner with dementiaThe 69-year-old stole the money from his victim after being made her power of attorney in 2014. Sinclair attempted to cover up his crimes by falsely insisting the woman had given him permission to transfer money to himself from her accounts.
Consulte Mais informação »
Aberdeen lawyer jailed for embezzling £120,000 from pensionerJohn Sinclair stole the money from a dementia sufferer after being named her power of attorney.
Consulte Mais informação »