What is the association between particulate matter exposure and SARS-CoV-2 infections? medrxivpreprint MonashUni SARSCoV2 COVID19 Infection ParticulateMatter
By Pooja Toshniwal PahariaNov 21 2022Reviewed by Aimee Molineux In a recent study posted to the medRxiv* preprint server, researchers assessed the association between particulate matter ≤2.5mm exposure and severe acute respiratory syndrome coronavirus 2 infection and severity outcomes such as hospitalizations and deaths.
About the study In the present systematic review, researchers reviewed existing literature on the association between PM2.5 air pollutant exposure and the risk of SARS-CoV-2 infection and severity outcomes. Studies were excluded if they utilized case-series, cross-sectional, ecological, in vitro, or animal-based study designs. Review, hypothesis, commentary, opinion articles, editorials, preprints, or conference presentations were excluded from the analysis. Studies that did not utilize PM2.5 as the study exposure or only investigated tobacco-generated smoke as an air pollutant or air pollution only in indoor settings were excluded.
As a result, only 18 studies with cohort designs were considered for the final analysis. The included studies used data from North America , Europe , and China. In addition, three studies only included individuals with a COVID-19 test report, whereas the other four infection studies either used cohorts irrespective of SARS-CoV-2 testing reports or analyzed the entire study cohort. Further, three studies used multiple predictors within one model. The period of measuring PM2.5 exposure considerably varied, from just seven days before inclusion or recruitment to almost 20 years.
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