The disorder can be inherited or triggered by certain conditions like an infection.
neurological symptoms, including irritability, fatigue, seizures and mental status changes
It can be common for people to need a blood transfusion because the red and white blood cell count can drop so low, Choi said. HLH be life-threatening because it involves multiple vital organs, including the brain, liver and lungs, he added. Patients are typically admitted to the ICU or at least hospitalized.Doctors can diagnose the condition with the help of blood tests or a genetic test, along with the presence of typical symptoms.
When patients are sick with acquired HLH, doctors treat the underlying condition that triggered the exaggerated immune response. Antibiotics or antiviral medications are given to treat an infection, for example. After the patient is stable, medications similar to chemotherapy are used to treat HLH, Choi said.
Patients with inherited HLH require a stem cell transplant “as early in life as possible,” the Genetic and Rare Diseases Information Center noted. This procedure is considered a cure for familial HLH.A. Pawlowski is a regular NBC News contributor focusing on health, travel and business news and features. Previously, she was a writer, editor and producer at CNN.
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