The National Institutes of Health on Monday said it’s launching trials to test drugs and other treatments for long COVID, a mysterious condition that affects millions of people after they catch the coronavirus.
The phase II trials will focus on four impacts of the condition, including the virus’ long-standing jolt on the immune system and bodily organs; cognitive ability; sleep and daytime drowsiness; and systems like breathing and heart rate.
Vaccine makers Pfizer and Moderna, which produce annual COVID-19 boosters, recently told Congress they will dramatically increase the list price of their shots now that the government is not guaranteeing purchases. Officials said the incidence of long COVID seemed higher during the delta wave of 2021 before dropping when the omicron strain hit. Sufferers say the condition has made it hard for them to earn a living or enjoy daily activities.
The trials will build on NIH’s RECOVER Initiative, which enrolled 24,000 people and collected millions of health records to examine why some people have lasting impacts from COVID-19. Each arm of the phase II trials will include 100 to 300 participants, though some might include more enrollees. The new initiative is divided into four categories, starting with a Vital category that looks at how the coronavirus lingers in some people, causing havoc on the immune system or the body’s organs.A branch of the study called Neuro will see if there are ways to correct cognitive problems from long COVID, including brain fog, memory problems and difficulty with attention, clear thinking and problem-solving.
NIH researchers said they plan to deploy at least seven more treatments or drugs in subsequent trials, once they are enrolled and launched.
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