Vaccine printer could help vaccines reach more people MIT NatureBiotech
MIT researchers have come up with a possible solution to this problem: a mobile vaccine printer that could be scaled up to produce hundreds of
The printer produces patches with hundreds of microneedles containing vaccine. The patch can be attached to the skin, allowing the vaccine to dissolve without the need for a traditional injection. Once printed, the vaccine patches can be stored for months at room temperature., the researchers showed they could use the printer to produce thermostable COVID-19 RNA vaccines that could induce a comparable immune response to that generated by injected RNA vaccines, in mice.
To get around this obstacle, the MIT team set out to find a way to produce vaccines on demand. Their original motivation, before COVID-19 arrived, was to build a device that could quickly produce and deploy vaccines during outbreaks of diseases such as Ebola. Such a device could be shipped to a remote village, a refugee camp, or military base to enable rapid vaccination of large numbers of people.
"When COVID-19 started, concerns about vaccine stability and vaccine access motivated us to try to incorporate RNA vaccines into microneedle patches," Daristotle says.
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