US government's WWII mobilization on penicillin is a road map to fighting the coronavirus

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US government's WWII mobilization on penicillin is a road map to fighting the coronavirus
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'Penicillin manufacturing in World War II shows that to have enough medical equipment and save the most lives, the US government needs to take the lead,' says peterubel in usatodayopinion

On March 14, 1942, an American soldier with bacteria coursing through his bloodstream was treated with penicillin, a new wonder drug that saved his life. That single treatment exhausted half the nation’s supply of the drug. Two years later, as U.S. troops prepared to launch the D-Day invasion, America hadDonald Trump refers to himself as a wartime president.

The history of penicillin manufacturing during World War II teaches an important lesson: If we hope to address the shortage of lifesaving medical equipment, and if we want to make sure available equipment is distributed in a manner that saves the greatest number of lives, the U.S. government needs to take the lead.Penicillin was critical to the U.S.

The penicillin mold was being grown on petri dishes, which yielded only tiny amounts of the drug. The antibiotic was so scarce that when patients received treatment, doctors collected their urine to retrieve any of the drug that passed through the urinary system intact, so they could purify the penicillin and infuse it back into the patients if necessary.

Even after war broke out, pharmaceutical companies were reluctant to manufacture the drug, in part because the science of making penicillin — growing large quantities of the mold and harvesting the byproduct — was outside their wheelhouse; most pharmaceutical companies use the tools of chemistry, not biology, to manufacture theirRecognizing industry wouldn’t solve the problem if left to its own devices, the U.S. government began coordinating large scale manufacturing efforts.

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