One breast cancer drug showed particular ability to reach tumors in the brain, which are notoriously tough to treat.
“HER2-positive”
Krop led a study of 253 such women to test the guided missile drug, called T-DXd, given as an infusion every three weeks. These women had tried six previous treatments, on average, before the experimental drug. Side effects were substantial, though. About 60% of women had low blood counts, nausea, anemia or fatigue, and 15% stopped treatment because of them.
Because these cancers generally prove fatal, the drug “is still beneficial for most patients,” he said., a breast cancer expert at the MD Anderson Cancer Center in Houston who wasn’t involved in the study, said it may be possible to give patients preventative anti-inflammatory medicines. That would be worth the risk because the drug’s benefit is so great, she said.
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