'My bones are black. Like, the bones in my body are black.'
, a person with alkaptonuria may begin to have joint issues in their 30s. They frequently the first experience lower back pain and stiffness, then knee, hip, and shoulder pain.These are osteoarthritis' initial signs and symptoms. Over time, cartilage, a resilient, adaptable tissue present throughout the body, may deteriorate and fracture, causing harm to the spine and joints. There may be a necessity for joint replacement surgeries.
"Currently, no reports exist of poor outcomes in the presence of this disease; however, surgeons should exclude alternative causes of bone discoloration when the history is unclear."
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