Thousands of unique arboviruses and flaviviruses identified from samples collected between 1954-2018 Arbovirus CellCulture Encephalitis RNA Virus eurotropic publichealth VirusesMDPI IEC_BR
By Dr. Priyom Bose, Ph.D.Apr 12 2023Reviewed by Benedette Cuffari, M.Sc. The Evandro Chagas Institute has isolated and classified virological and serological data for over 80 years. Around 200 types of arboviruses have been isolated and classified by the IEC, some of which have not been taxonomically classified.
Study: Isolation of Flaviviruses and Alphaviruses with Encephalitogenic Potential Diagnosed by Evandro Chagas Institute in the Period of 1954–2022: Six Decades of Discoveries. Image Credit: angellodeco / Shutterstock.com Related StoriesAt present, seven viral families of arboviruses, including Asfaviridae, Rhabdoviridae, Flaviviridae, Phenuiviridae, Sedoreoviridae, Togaviridae, and Peribunyaviridae have been shown to be capable of infecting humans and animals. Among these, the West Nile virus , Chikungunya virus , Dengue virus , Rocio virus , and Zika virus are neuroinvasive viruses with high epidemiological interest in Brazil.
The genus Flavivirus belongs to the family Flaviviridae and is composed of 53 viruses, including the Japanese encephalitis virus , WNV, ZIKV, and DENV. These viruses also contain a positive-sense RNA genome with an icosahedral symmetrical structure. Flaviviruses are transmitted through cycles between vectors and vertebrate hosts.
In addition to isolating viruses from cell cultures, viruses with encephalitogenic potential were isolated from infected mice and mosquitoes. Taken together, 1,347 arbovirus samples with encephalitogenic potential were isolated from mice, 639 of which were Flaviviruses and 708 were Alphaviruses were isolated.
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