The Next Generation of Wellness Brands Is Using DNA to Create Hyper-Customized Supplements

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The Next Generation of Wellness Brands Is Using DNA to Create Hyper-Customized Supplements
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This is as personalized as it gets:

Author:Jessica L. YarbroughPublish date:Sep 26, 2019I just took a DNA test: Turns out, my NQO1 gene is 100% inactive. My results don't exactly roll off the tongue à la Lizzo's lyrics — but they are, at least, actionable. The stat is one of 52 genetic markers that supplement company Rootine takes into account each time it formulates my personalized pack of daily multivitamins.

It's true that all humans, to some extent, have the same basic nutritional needs — recommended Daily Values are a thing for a reason — but there are a surprising number of mutations and markers that render generic DVs useless. Rootine checks for "52 genetic variations that have a proven impact on nutrient needs" when analyzing saliva samples from customers' at-home DNA testing kits, says co-founder Rachel Sanders.

This evidence-based approach seems straightforward and infallible , but — as with so many wellness innovations — it is not. "It's very difficult to determine how much vitamins or nutrients an individual needs strictly based on DNA," says Dr. Firshein. That's why Baze, a new startup backed by old-school vitamin company Nature's Way — to the tune of $6 million in Series A funding — creates custom vitamins based on at-home blood tests.

Dr. Firshein is a fan of combining both technologies, saying, "I use DNA testing along with blood testing routinely in my practice, and I do feel it has added a critical dimension to how I treat my patients." Lekhraj assesses her clients' nutritional needs by considering a host of indicators: DNA, blood, diet, current lifestyle, personal history and preferences and "other factors including methylation and metabolism.

As lovely as that sounds, I have to address double-helix-shaped elephant in the room: data. Services like Ancestry.com and 23andMe have shone a light on the potential dangers of sharing your DNA with genetic testing companies: Since the field is relatively new, there aren't many laws around genetic privacy. There are concerns your DNA may be sold to third parties, including marketers and "Big Pharma" .

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