FDA Approves First Monoclonal Antibody Treatment for Preventing COVID-19, AstraZeneca’s Evusheld
, which can be used by high-risk patients before they’re exposed to influenza). Many treatments are even more effective when administered before exposure, not after, Fuller notes. But more research is needed before the FDA can give its full approval to Evusheld, Dr. Gupta explains.People 12 and older who are immunocompromised and have not been recently infected with or exposed to SARS-CoV-2 are eligible for Evusheld, the FDA says.
People who have a history of “severe adverse reactions” to the COVID-19 vaccines or any components of those vaccines, a very small population, can also receive the antibody therapy. This group does not encompass those who refuse to receive the vaccine for non-life-threatening reasons.There is much we don’t yet know about the emerging Omicron variant of SARS-CoV-2, including how well monoclonal antibodies will respond to it.
has so many mutations to its spike protein, the part of the virus the antibodies target—it’s a question researchers are racing to answer, Dr. Razonable says.
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