The Disturbing Reason a Man's Voice Grew Hoarse Over a Year Without a Clear Cause
JAMA Otolaryngology–Head & Neck Surgery
, the man appeared otherwise healthy when he went to a clinic in Pennsylvania that treats conditions of the head and neck. The man, in his 60s, reported that he'd developed"progressively worsening hoarseness" and shortness of breath over the past 12 months. His primary care physician had previously treated him with inhaledTo examine the man's vocal folds and larynx, the hollow"voice box" that holds the vocal folds, doctors used a high-speed imaging technique called videostroboscopy.
The doctors also performed a biopsy on tissue from the man's larynx and confirmed that the tissue was swollen, irregular, and"friable" to the touch, meaning it tore easily. A close-up examination of the sampled tissue revealed patches of dead laryngeal cells surrounded by clusters of
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