Surgeons withdraw support for heart disease advice

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Surgeons withdraw support for heart disease advice
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European guidelines on a form of heart disease are under review, following a Newsnight investigation.

The trial called Excel started in 2010 and was sponsored by big US stent maker, Abbott.

In 2016, the results of the trial for patients three years after their treatments were published in the prestigious New England Journal of Medicine. The article concluded stents and heart surgery were equally effective for people with left main coronary artery disease.Newsnight has seen that unpublished data and it shows that under the universal definition, patients in the trial that had received stents had 80% more heart attacks than those who had open heart surgery.

"It is a matter of serious concern to us that some results in the Excel trial appear to have been concealed and that some patients may therefore have received the wrong clinical advice," Prof Domenico Pagano, EACTS secretary general, said. However, the main investigators chose not to do so at the time. They point out that the board allowed the trial to continue unchanged.

This found for every 100 who died after having open heart surgery, 135 people with stents died. Overall, 10% of people who had surgery died in the trial compared with 13% who had stents.

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