Study shows 44% of global cancer deaths are preventable Cancer GlobalDisease Disability Mortality Tobacco Alcohol TheLancet
By Dr. Sanchari Sinha Dutta, Ph.D.Aug 24 2022Reviewed by Benedette Cuffari, M.Sc. A recent study published in The Lancet has estimated the global cancer burden triggered by behavioral, environmental, occupational, and metabolic risk factors. The study findings reveal that behavioral risk factors are major contributors to the global cancer burden in 2019. In addition, the largest induction in metabolic risk factors has been observed between 2010 and 2019.
The Global Burden of Diseases, Injuries, and Risk Factors Study is a large-scale study to estimate the cancer burden caused by a broad set of modifiable risk factors. This study estimates the cancer burden over time for all countries across the globe, for all age groups, and for both males and females.
The GBD 2019 comparative risk assessment framework was utilized to estimate the fraction of the cancer burden caused by each risk factor. A total of 82 cancer risk-outcome pairs were included in the analysis. Regarding cancer disability-adjusted life-years, tobacco use is the leading behavioral risk factor in males in 2019, followed by alcohol use, dietary risks, and air pollution. In females, tobacco use was also the leading risk factor associated with cancer disability-adjusted life-years, which was followed by unsafe sex, dietary risks, overweight/obesity, and diabetes.
A relatively higher fraction of risk-attributable cancer death was observed in males as compared to that in females. By excluding gender-specific cancers, smaller male-to-female ratios for risk-attributable cancer deaths were observed in countries with a higher socio-demographic index , which is a composite index per capita income, educational attainment, and total fertility rate in a country.
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