itemprop=description content=Developing brains become shaped by the sights, sounds, and experiences of early life. The brain's circuits grow more stable as we age.
Oct 5 2023 Developing brains become shaped by the sights, sounds, and experiences of early life. The brain's circuits grow more stable as we age. However, some experiences later in life open up opportunities for these circuits to be rapidly rewired. New research from Cold Spring Harbor Laboratory Associate Professor Stephen Shea helps explain how the brain adapts during a critical period of adulthood: the time when new mothers learn to care for their young.
It's not lost on us that Rett syndrome patients have difficulty interpreting and producing language. Difficulties with communicating are widespread in autism spectrum disorders. One of the reasons we study Rett syndrome is that this may be a valuable model for other forms of autism." The Shea lab's studies of MECP2 began about 10 years ago when he first learned that female mice with mutations in the Mecp2 gene are poor parents.
Related StoriesShea points out that PV neurons also play an essential role in brain circuits earlier in life. These cells normally dampen the signals of other neurons. But they release this inhibition during development, creating conditions that are favorable for change. Shea says:
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