According to a study recently published in the Journal of Clinical Oncology, South Carolina is experiencing one of the most significant increases in anal cancer incidence among women and anal cancer deaths among men. The study was led by Ashish Deshmukh, Ph.D., a researcher at MUSC Hollings Cancer C
Anal cancer is a type of cancer that affects the tissues of the anus, which is the opening at the end of the rectum. It is a rare type of cancer, however, its incidence has been increasing in recent years., South Carolina is experiencing one of the most significant increases in anal cancer incidence among women and anal cancer deaths among men. The study was led by Ashish Deshmukh, Ph.D.
“Anal cancer is often neglected and stigmatized. Also, it has been historically perceived as a rare malignancy,” said Deshmukh, who seeks to change the public perception, given the dramatic increase in the disease incidence and death rates that the U.S. is seeing. Nearly 10,000 new cases and over 1,600 deaths are expected to be attributed to anal cancer in 2022.
This paper also identifies key contributors to the rise in anal cancer among men and women. In states where HIV was more common, anal cancer incidence was greater among men. State-level incidence patterns were correlated with smoking among women. “HIV infection enhances the cancer-causing effects of HPV, leading to more rapid anal cancer development. Our study suggests that smoking may also be an important anal cancer risk factor among women,” Deshmukh added.
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