A creative integration of AI-assisted imaging with the technology of an outdated inkjet printer results in a more efficient and cost-effective method for detecting bacteria in substances such as blood and wastewater. By shining a laser on a drop of blood, mucus, or wastewater, the reflection of t
, and more,” said Jennifer Dionne, an associate professor of materials science and engineering and, by courtesy, of radiology at
Details of the printed dots on a gold-coated slide where false coloring in the close-up of a single dot shows red blood calls in red andbacteria in blue. The researchers also printed onto an agar-coated slide to show how the dots fare under incubation.
“The key to separating bacterial spectra from other signals is to isolate the cells in extremely small samples. We use the principles of inkjet printing to print thousands of tiny dots of blood instead of interrogating a single large sample,” explained co-author Butrus “Pierre” Khuri-Yakub, a professor emeritus of electrical engineering at Stanford who helped develop the original inkjet printer in the 1980s.
“It’s an innovative solution with the potential for life-saving impact. We are now excited for commercialization opportunities that can help redefine the standard of bacterial detection and single-cell characterization,” said senior co-author Amr Saleh, a former postdoctoral scholar in Dionne’s lab and now a professor at Cairo University.
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