As the diabetes drug Ozempic gains more attention, a surprising side effect has emerged: the desire to drink less alcohol. Scientists want to know why.
As the diabetes drug gains more attention, a surprising side effect has emerged.
A part of her missed the comforting blur from being tipsy. When she tried to drink while on Ozempic, though, she felt dizzy and nauseated — but not intoxicated. “I was just incapable of feeling the buzz,” said Monsen, who lives in Seattle. Now, she barely drinks at all.As Ozempic gains more attention and more people use the diabetes drug off-label to lose weight, doctors say that many patients are reporting similar experiences: They start the medication and then stop wanting to drink alcohol.
Even during a birthday lunch, the type of social event where she would typically enjoy a cocktail or two, she couldn’t bring herself to drink. She ended up ordering tea. “I just wasn’t expecting it,” she said of her new distaste for alcohol. But she said she was grateful for the push to cut back on drinking.Scientists are working to understand why people like Zarpour experience this side effect.
A few human studies on alcohol and medications like Ozempic are underway. Researchers in Denmark recently published the results of a clinical trial that tested another GLP-1 receptor agonist in patients with alcohol use disorder. The study included nearly 130 people and examined whether those who received the compound, alongside cognitive behavioral therapy, drank less than those who received a placebo and therapy.
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