Simultaneous radiation and immunotherapy found to be beneficial for a subset of lung cancerpatients NatureGenet naturecancer
aneuploidy were found to have significantly better survival if RT was added to ICB. By contrast, there was no survival benefit for patients with low aneuploidy when adding RT to ICB treatment.
"A key observation was that radiation therapy alone caused depletion of important immune cells within the tumor, however, with concurrent therapy there was enrichment of immune cells and improved elimination of tumor cells that led to positive survival outcomes in mNSCLC patients," Pitroda said. Tumors with a high degree of aneuploidy had a worse prognosis because these patients did not respond to immunotherapy alone. In addition, tumor aneuploidy complemented tumor mutational burden —an established biomarker across many cancers for immunotherapy response. Patients with high TMB often respond well to immunotherapy, and patients with low TMB usually do not.
Brasil Últimas Notícias, Brasil Manchetes
Similar News:Você também pode ler notícias semelhantes a esta que coletamos de outras fontes de notícias.
Recent food hygiene scores for Watford's restaurants and cafesThe latest food hygiene ratings from around Watford have been released following visits from inspectors.
Consulte Mais informação »
Driver caught on hard shoulder 'waiting for relative to land' at airportPolice have shared numerous pictures of drivers parked up on the hard shoulder in recent months
Consulte Mais informação »
New technologies and recent advances in the study of T cells and T-cell epitope discovery in food allergy researchNew technologies and recent advances in the study of T cells and T-cell epitope discovery in food allergy research jacionline ljiresearch Tcell foodallergy allergy allergies immunity immunology
Consulte Mais informação »
Nanoparticles displaying SARS-CoV-1 and SARS-CoV-2 spikes induce broad antibody responses in animal modelNanoparticles displaying SARS-CoV-1 and SARS-CoV-2 spikes induce broad antibody responses in animal model Antibody Nanoparticles SARS SARSCoV2 Coronavirus Disease COVID iScience_CP UW WeillCornell UvA_Amsterdam scrippsresearch
Consulte Mais informação »