Following reports of self-injury and suicidal thoughts among a small number of people who’ve taken Ozempic or Wegovy in Europe and the UK, health regulators are investigating whether the drugs carry a risk of these side effects.
Chelsea Stahl / NBC News; Getty ImagesFollowing reports of self-injury and suicidal thoughts among a small number of people who’ve taken Ozempic or Wegovy in Europe and the United Kingdom, health regulators there are investigating whether the drugs carry a risk of these side effects.last month that it was reviewing 150 such reports from people who took drugs in this class, called GLP-1 receptor agonists, which lower blood sugar and suppress appetite by mimicking a hormone in the gut.
She started taking Ozempic off-label for weight loss in late June. Although this application of the medication has become somewhat common, Novo Nordisk, the drug’s maker, has said it does not promote or encourage it and leaves such decisions to doctors’ discretion.“I was starting to have some pretty low feelings — not suicidal, but just very low, just thinking about all the crap that I’ve gone through this last year,” she said.
Had she continued taking the medication, Stainer said, it’s possible her mental state would have become worse. Anecdotes like Stainer’s have created a conundrum for regulators in the U.S. and abroad: Though some patients have described severe psychological reactions to GLP-1 receptor agonists, doctors aren’t noticing a trend and clinical trials don’t suggest that these side effects are correlated with the drugs.
Bruce said she had shared her history of mild depression with the telehealth doctor who prescribed her Wegovy but was not told about any mental health side effects.
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