SGLT-2 inhibitors and in-stent restenosis-related events after acute myocardial infarction: an observational study in patients with type 2 diabetes - BMC Medicine

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SGLT-2 inhibitors and in-stent restenosis-related events after acute myocardial infarction: an observational study in patients with type 2 diabetes - BMC Medicine
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A study published in BMCMedicine finds that the use of SGLT2i is associated with a reduced incidence of cardiovascular events related to intra-stent restenosis in patients with type 2 diabetes.

]. Furthermore, patients answered a specific questionnaire about medicines used for diabetes treatment before the beginning of the study, the date of the beginning and end of therapy, the route of administration, and the duration of use. Information from the medicine inventory during the research and this specific questionnaire was used to classify patients as “never SGLT2i-users” and “current SGLT2i-users.

Based on the detected contours proximal and distal from the lesion region, a reference area function was derived modeling the tapering of a healthy vessel. From these data, the following cross-sectional CTCA-derived parameters were automatically provided by operators: minimum lumen area , and % area stenosis at the level of the MLA defined by [1-MLA/corresponding reference lumen area) × 100]. Minimum lumen diameter , less accurate parameter, was not considered.

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