The study utilized several existing datasets to explore the neural basis of various psychiatric disorders and discovered a common network for all of them. Nearly one in five adults in the United States is affected by psychiatric disorders such as schizophrenia and depression. Additionally, about
The team identified a brain network that is common for all psychiatric illnesses. This discovery opens up new opportunities for future research, such as looking at brain scans to see if the same circuit is active and comparing differences between psychiatric disorders using this circuit.
“Neurology asks: ‘Where is the lesion?’ and psychiatry asks: ‘What are the symptoms?’ We now have tools to explore the ‘where’ question for psychiatry disorders. In this study, we examined whether psychiatric disorders share a common brain network.” In subsequent analyses of a dataset including brain imaging from 194 veterans with and without penetrating head trauma along with their psychiatric diagnoses, the researchers overlayed lesions onto the transdiagnostic network and found that lesion-induced damage in the network correlated with a higher likelihood of multiple psychiatric illnesses. They also used the veteran data to independently derive a transdiagnostic network based on brain lesions associated with psychiatric illness.
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