Becoming a full-fledged organism out of a handful of cells, complete with functioning tissues and organs, is a messy yet highly synchronized process that requires cells to organize themselves in a precise manner and begin working together.
"It was like somebody had flipped on a switch," Cohen described.
Interestingly, the heartbeats started from different spots in different zebrafish, suggesting that there's nothing unique about the cells that fire first. This finding was counterintuitive because cells in adult hearts behave differently. "The heart first learns how to keep pace without a clock, and individual cells first learn to cooperate without agreeing on what their roles are," Jia added."It is very important for the heartbeat to be regular, but it is organized very quickly at the start of life from what seems to be a total mess."
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