Preventing spread of parasitic DNA in our genomes

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Preventing spread of parasitic DNA in our genomes
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Researchers have identified a new enzyme called PUCH, which plays a key role in preventing the spread of parasitic DNA in our genomes. These findings may reveal new insights into how our bodies detect and fight bacteria and viruses to prevent infections.

The research teams of Professor René Ketting at the Institute of Molecular Biology in Mainz, Germany, and Dr. Sebastian Falk at the Max Perutz Labs in Vienna, Austria, have identified a new enzyme called PUCH, which plays a key role in preventing the spread of parasitic DNA in our genomes. These findings may reveal new insights into how our bodies detect and fight bacteria and viruses to prevent infections.

How do our cells combat these internal enemies? Fortunately, our cells have evolved a genomic defense system of specialized proteins whose job it is to hunt down TEs and prevent them from replicating. In a new paper published in, René Ketting and Sebastian Falk together with their research teams report their discovery of PUCH -- a completely new, previously unknown type of enzyme, which is key to this genomic defense system.

Researchers reveal new details about a key enzyme that makes DNA sequencing possible. The finding is a leap forward into the era of personalized medicine when doctors will be able to design ...

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