A study conducted in Taiwan and published in BMCRheumatol finds that subjects with systemic lupus erythematosus, especially those in the sixth to ninth year after diagnosis, are at a higher risk of ischemic heart disease.
]. However, there was a difference in the study populations, as we recruited not only myocardial infarction patients but also angina patients. The severity and lethality were more serious in myocardial infarctions than in angina, which might contribute to the difference in results.
Women with diabetes have a greater relative risk of cardiovascular disease compared with their male counterparts []. In the present study, diabetes was a significant risk factor in the control subjects who developed IHD, but not a significant risk factor for developing IHD in the SLE group, which is inconsistent with previous findings. Differences in study populations and ethnicity might explain this difference.
]. However, patients with SLE from the same age group were at a higher risk of IHD , indicating that SLE might increase the susceptibility of this population to IHD.Subjects with SLE were at a higher risk of IHD, especially those in the 6th to 9th year after SLE diagnosis.
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