Possible association between air pollution exposure, especially at young age, and alterations in brain structure ISGLOBALorg ELSenviron
has found an association, in children aged 9‑12, between exposure to air pollutants in the womb and during the first 8.5 years of life and alterations in white matter structural connectivity in the brain. The greater the child's exposure before age 5, the greater the brain structure alteration observed in preadolescence. The study was led by the Barcelona Institute for Global Health .
Tracts or bundles of cerebral white matter ensure structural connectivity by interconnecting the different areas of the brain. Connectivity can be measured by studying the microstructure of this white matter, a marker of typical brain development.
"A larger putamen has been associated with certain psychiatric disorders ," says Anne-Claire Binter, ISGlobal researcher and first author of the study. "The novel aspect of the present study is that it identified periods of susceptibility to air pollution," Binter goes on to explain."We measured exposure using a finer time scale by analyzing the data on a month-by-month basis, unlike previous studies in which data was analyzed for trimesters of pregnancy or childhood years. In this study, we analyzed the children's exposure to air pollution from conception to 8.5 years of age on a monthly basis.
To determine each participant's exposure to air pollution during the study period, the researchers estimated the daily levels of nitrogen dioxide (NO
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