Pfizer is testing a 3rd dose in kids: What parents need to know

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Pfizer is testing a 3rd dose in kids: What parents need to know
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Pfizer is testing a third dose of its COVID-19 vaccine in kids. Here's what parents need to know about what's next for the company's pediatric vaccine.

"In my mind, delta is definitely playing a role because the initial studies were done on alpha for the dosing," Li said. “We know that there is

— not a horrible one, but a little bit of a reduction — against delta, and that definitely is playing a part.”add a third dose of the vaccine rather than start again with two larger doses for 2- to 4-year-olds is based on the safety and tolerability profile of the 3 microgram dose for kids in this age group, Kathrin U. Jansen, Pfizer's senior vice president and head of vaccine research and development, said on aThis approach generally also reflects researchers' evolving understanding that the vaccine requires a"three-dose schedule rather than a two-dose schedule" to be most effective, Moss said.

Another part of the decision may simply be coming out of a need for expediency amid the COVID-19 crisis."If you were to up the amount, you literally would have to re-recruit a whole new group of ," Li explained."You would also have to redo your initial phase 1 studies." Instead,"this is something they can add on to the ongoing trial and not have to re-recruit," Moss explained."And that helps with the timeline."Still, the company said there will be a delay. Initially, Pfizer expected to have results by the end of the year and be submitting a request for an FDA authorization shortly after.

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