PFAS chemicals in water and consumer goods linked to rising thyroid cancer rates

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PFAS chemicals in water and consumer goods linked to rising thyroid cancer rates
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Study published in eBioMedicine reveals that exposure to certain per- and polyfluoroalkyl substances (PFAS) significantly increases the risk of thyroid cancer.

By Dr. Sanchari Sinha Dutta, Ph.D.Oct 25 2023 A study published in the journal eBioMedicine finds that exposure to per- and polyfluoroalkyl substances can increase the risk of thyroid cancer in human populations.

Endocrine-Disrupting Chemicals: A Growing Concern Excessive exposure to endocrine-disrupting chemicals is believed to be a potential risk factor associated with increased incidence of thyroid cancers. Per- and polyfluoroalkyl substances are a group of endocrine-disrupting chemicals used in industries and consumer products since the 1940s.

Study design A total of 88 adult thyroid cancer patients with plasma samples collected at or before the cancer diagnosis were enrolled in the study. Among these patients, 74 had papillary thyroid cancer. The control study population included 88 healthy individuals who were pair-matched on age, sex, ethnicity, body mass index, smoking status, and year of sample collection.

Considering the patients with papillary thyroid cancer, a similar positive association was observed between linear-PFOS intensity and thyroid cancer diagnosis rate. Why PFAS Are Carcinogenic The study finds that exposure to endocrine-disrupting chemicals like PFAS can increase the risk of thyroid cancers. Among various PFAS, the most potent contributors are linear PFOS, branched PFOS, perfluorononanoic acid, perfluoro-octyl-phosphonic acid, and linear perfluoro-hexane-sulfonic acid.

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