Paxlovid antiviral therapy reduces risk of long COVID Paxlovid Antiviral Nirmatrelvir Ritonavir PASC LongCOVID medrxivpreprint STLOUISVA VREFSTL WUSTLme WUSTLpubhealth
Study: Nirmatrelvir and the Risk of Post-Acute Sequelae of COVID-19. Image Credit: p.ill.i / Shutterstock
In December 2021, oral nirmatrelvir received approval for the treatment of acute SARS-CoV-2 infection in the United States . Millions of hospitalized people are at risk of progression to severe diseases benefitted from its treatment. However, there is still a lack of data regarding this drug's efficacy in reducing the risk of long COVID.
The nirmatrelvir group comprised 9424 participants who received nirmatrelvir within five days of T0 and survived the first 30 days after the first positive SARS-CoV-2 test. The control group had 47,123 individuals who received no COVID-19 treatment during the acute COVID-19 phase and survived 30 days after T0.
Study findings Related StoriesOf the total study population, 9217 individuals received oral nirmatrelvir treatment within five days after T0, and the team followed up with them and 47,123 controls to August 31, 2022. The authors noted that the nirmatrelvir treatment was associated with reduced risk of PASC, with HR and ARR of 0.74 and 2.32, respectively. Additionally, it reduced the risk of 10 of 12 post-acute COVID-19 outcomes.
Brasil Últimas Notícias, Brasil Manchetes
Similar News:Você também pode ler notícias semelhantes a esta que coletamos de outras fontes de notícias.
Long Covid patients still battling virus as third anniversary of infection nearsSome of the UK’s earliest long Covid patients are still battling the condition nearly three years after first getting infected.
Consulte Mais informação »
Biggest-ever NHS nurses strike 'would hit A&E patients' and worsen Covid backlogAround 300,000 nurses are thought to have voted in favour of industrial action in the first of a potential cascade of strikes
Consulte Mais informação »
What went wrong with the UK economy, from Brexit and Covid to Russia's war in UkraineBritain’s economy is on shaky ground, with the Bank of England indicating that stability is a long way off 🔎 But what exactly went wrong? SerinaSandhu1 explains
Consulte Mais informação »
New Leeds hospital data shows rising Covid patients figure but key statistic fallsNearly 150 people were being treated in hospital for Covid in Leeds last week, according to new NHS figures.
Consulte Mais informação »