Until now, lung transplants on patients with advanced lung cancer have been rare operations
. Typically, patients with cancer are not eligible to receive organ transplants because it’s feared that the cancer will recur after the transplant. Patients who receive new organs must take medication to suppress their immune systems, which can lead to a recurrence if any cancer cells are left in the body.
“Most COVID transplants we did had tons of bacteria in them,” Bharat said. “We felt if we could carefully remove those lungs and transplant them, we probably should be able to do the same in cancer ridden lungs.” Not all patients with lung cancer are eligible for the surgery. The surgery is only for patients whose cancer has not spread beyond their lungs and who have run out of other treatment options, such as chemotherapy, radiation, immunotherapy and other surgeries.
Khoury underwent the 7-hour-long surgery in September 2021. Khoury, who was a nonsmoker, said he was told by doctors at other health systems that he wouldn’t survive. Before the transplant at Northwestern, he was on a ventilator and had developed pneumonia and sepsis. When he got a transplant, he likely only had days left to live, said Dr. Young Chae, a medical oncologist with Lurie Cancer Center at Northwestern Medicine.Meanwhile, Ameli was diagnosed with stage 4 lung cancer in January 2022.
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