Researchers found that a new blood test for sepsis could save lives and money.
Sepsis is a life-threatening medical emergency that occurs when an infection causes a chain reaction throughout the body that can lead to the failure of multiple organs in rapid succession. In the United States about 350,000 people die from sepsis each year, according to the Centers for Disease Control and Prevention, making proper diagnosis a matter of life-or-death importance.
"One of the tools that health economists use frequently is decision modeling," Hollenbeak said."In decision modeling, we use a mathematical model to calculate the likely outcome and cost of a specific decision. In this case, we evaluated the cost and benefit of using the IntelliSep test on patients who are suspected to have sepsis.
Procalcitonin is a biomarker that the body releases in response to infection. It can be measured with a simple blood test. Studies have shown that procalcitonin levels can be used to help diagnose sepsis, but procalcitonin only indicates the presence of infection and not the inflammation associated with sepsis.
"For patients who have sepsis, getting sent home from the hospital is very serious because they can suffer multiple-organ failure within hours," Hollenbeak said."Every year, there are patients who enter the emergency department of a hospital, present with a limited number of sepsis symptoms and are sent home. This test could save many of those people's lives."
Cytovale, the manufacturer of the IntelliSep test, funded the study. The company played no role in the design or execution of the study or interpretation of results. This research was independently peer-reviewed and published.Christopher S. Hollenbeak, Daniel J. Henning, Glenn K. Geeting, Nathan A. Ledeboer, Imran A. Faruqi, Christi G. Pierce, Christopher B. Thomas, Hollis R. O’Neal.
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