A research study conducted by Hai-Lei Wei's research team at the Chinese Academy of Agricultural Sciences in China has revealed significant insights into the biosynthesis and modulation of plant immunity by a novel cyclic lipopeptide called medpeptin, produced by Pseudomonas mediterranea.
, shed light on the intricate structure–function interactions of cyclic lipopeptides and open new avenues for the development of plant disease resistance strategies.
The study highlights the critical role of a cell-wall leucine-rich repeat extensin protein and a receptor-like protein kinase in mediating medpeptin-triggered cell death and resistance to pathogen infection. Silencing these proteins compromised theThe identification of medpeptin and its unique mode of action provides valuable insights into the noncanonical mechanisms of CLP sensing and their impact on plant immunity.
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