Studies on fish suggest that delaying the use of medication may be beneficial for humans. According to new research from the University of Alberta, it may be better to allow a mild fever to run its natural course rather than immediately resorting to medication. The researchers discovered that al
New University of Alberta research suggests that allowing a mild fever to run its course may have health advantages, as untreated moderate fever in fish helped clear infections rapidly and controlled inflammation. Although the benefits of natural fever for humans still require confirmation, the researchers believe that similar benefits are likely due to shared fever mechanisms across the animal kingdom.
Moderate fever is self-resolving, meaning that the body can both induce it and shut it down naturally without medication, Barreda explains. The health advantages of natural fever to humans still have to be confirmed through research, but the researchers say because the mechanisms driving and sustaining fever are shared among animals, it is reasonable to expect similar benefits are going to happen in humans.
Using a custom swim chamber to study how fish responded behaviourally to fever, researchers Daniel Barreda, Amro Soliman, Farah Haddad, and their team found that mild fever helped the fish clear their bodies of infection rapidly, controlled inflammation, and repaired tissue damage. Credit: University of Alberta
For the study, fish were given a bacterial infection and their behavior was then tracked and evaluated using. Outward symptoms were similar to those seen in humans with fever, including immobility, fatigue, and malaise. These were then matched to important immune mechanisms inside the animals.
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