“Such a high number of [viral] mutations is notable,” said one expert. “These massive shifts, which we also saw from Delta to Omicron, are worrisome.”
As COVID-19 cases continue to rise nationwide, a new variant dubbed “Pirola” has experts worried.
“Such a high number of mutations is notable,” Roberts said. “When we went from XBB.1.5 to EG.5, that was maybe one or two mutations. But these massive shifts, which we also saw from Delta to Omicron, are worrisome.”The three biggest questions now facing medical experts are: how transmissible Pirola is, will it bypass existing immune defenses, and how lethal it will be for those unlucky enough to get infected by it.“Nobody knows right now, but studies are ongoing,” Roberts said.
The rapid spread of Pirola “doesn’t look good right now,” Dr. Eric Topol, director of the Scripps Research Translational Institute in La Jolla, Calif.,Pirola’s multiple mutations make it “radically different in its structure” compared to earlier coronavirus variants, Topol said. “CDC is closely monitoring hospitalization rates to identify any potential early signals that the BA.2.86 variant is causing more severe illness.”Our current levels of immunity, whether from vaccination or prior infection, also remain to be seen.
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