A new study on mice suggests the cause of Alzheimer's disease may not be the buildup of beta-amyloid clumps in the brain but rather breaks in the connections (synapses) between brain cells.
disease may not be the buildup of beta-amyloid clumps in the brain but rather breaks in the connections between brain cells.
By manipulating the natural processes of RNA editing in mice modelled to reflect Alzheimer's symptoms, researchers prevented the connections in their brains from breaking down. Memory was restored without removing the protein clumps that are thought to cause the disease, suggesting damage between neurons was a critical problem.
The finding provides a new understanding of Alzheimer's disease and an approach that could potentially address memory loss in Alzheimer's patients."People living with Alzheimer's experience a loss of these nerve cell connections which has been speculated to cause debilitating loss of memory that is synonymous with the disease,""We now have compelling evidence, in a model of Alzheimer's, that preventing the breakdown in these synapses is possible.
A multi-talented molecule that helps process genetic information, RNA goes through changes even after it's produced that can affect how it functions., involves changing its sequence, which could in turn affect how the protein it encodes works. This editing process happens a lot in the brain and is important for how memories work.to RNA editing not working properly. In Alzheimer's, changes in memory-related synapses are linked to cognitive decline.
Brasil Últimas Notícias, Brasil Manchetes
Similar News:Você também pode ler notícias semelhantes a esta que coletamos de outras fontes de notícias.
New wireless brain implants could bring mind control to new level: studyYou might soon be able to control your electronic devices using only your mind. A recent study published in the journal Nature Electronics shows that scientists are one step closer to an invention …
Consulte Mais informação »
Massive Study Pinpoints Specific Gut Bacteria Linked to Alzheimer'sTensions between the brain, the gut, and the makeup of its microbial inhabitants appear to play a critical role in the development of neurodegenerative conditions.
Consulte Mais informação »
Women who have nighttime hot flashes may be at greater risk for Alzheimer’s, study findsA greater number of nighttime hot flashes was associated with an increased likelihood of the disease, the study found.
Consulte Mais informação »
New 'supercontinent' could wipe out humans and cause Earth uninhabitable, study suggestsScientists conclude that a new 'supercontinent' could wipe out humans and all other mammals still alive in 250 million years due to 'a triple whammy,' based on a new study.
Consulte Mais informação »
New study on how governments can fund radical ecological and social policies without GDP growthAccording to a new study led by a researcher at Freie Universität Berlin's Otto Suhr Institute of Political Science, the level of gross domestic product (GDP) has no impact on the ability of states with monetary sovereignty to fund investments in radical decarbonization measures and ambitious social policies such as universal public services and a job guarantee. The study, 'How to pay for saving the world: Modern Monetary Theory for a degrowth transition,' has just been published in the journal Ecological Economics.
Consulte Mais informação »
Sasol moves to improve coal quality, study for new destoning unit completedJSE-listed energy group Sasol has confirmed that its planned new destoning unit, which has the potential to improve the quality of coal at its mines, will be on line towards the end of 2025 or early 2026. The capital required for this project will be confirmed at the financial investment decision, with environmental permit approval expected in the second half of next year.
Consulte Mais informação »