It has been described as “bringing your army right to the enemy.”
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Talquetamab was tested in phase 1 and phase 2 trials. The study participants had all been previously treated with at least three different therapies without being able to achieve lasting remission.“This means that almost three-quarters of these patients are looking at a new lease on life,” said Ajai Chari, MD, Director of Clinical Research in the Multiple Myeloma Program at The Tisch Cancer Institute and lead author of both studies.
The new treatment’s Phase 1 clinical trial enrolled 232 patients while its phase 2 trial included 143 patients treated on a weekly dose and 145 patients treated at a higher biweekly dose. The overall response rate in these two groups was about 73 percent.In addition, more than 30 percent of patients in both groups had a complete response or better, and nearly 60 percent had a “very good partial response” or better .The time it took to notice a response was on average 1.
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