Doctors on Wednesday reported unusually good results from tests of two experimental drugs in women with an aggressive form of breast cancer that had spread widely and resisted many previous treatments
SAN ANTONIO — .
"It's a guided missile. It's able to bring the chemotherapy directly to the cancer cell," said the study leader, Dr. Ian Krop of the Dana-Farber Cancer Institute in Boston. Krop led a study of 253 such women to test the guided missile drug, called T-DXd, given as an infusion every three weeks. These women had tried on average six previous treatments before the experimental drug. Different doses were tested, and 184 women got what turned out to be the best one. Among those women, 61% saw their tumors shrink at least 30%. In 6% of them, no signs of cancer were seen in at least two followup scans.
Because these cancers generally prove fatal, the drug"is still beneficial for most patients," he said. Dana-Farber's Dr. Eric Winer helped lead a study of the other experimental medicine — tucatinib, from Seattle Genetics.
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